Relapses in multibacillary leprosy patients after Multidrug therapy
نویسندگان
چکیده
منابع مشابه
Relapses in multibacillary leprosy patients after multidrug therapy.
OBJECTIVES To determine the magnitude of relapses in multibacillary leprosy patients after multi-drug therapy and to determine the factors influencing the relapse. DESIGN A retrospective study pertaining to multibacillary leprosy patients treated with MBMDT as per WHO guidelines was carried out. The study included 300 MB patients who had successfully completed treatment during 1986-2002, of w...
متن کاملRelapses in multibacillary leprosy patients: effect of length of therapy.
Two groups of MB leprosy patients, one treated to the point of smear negativity (TSN) and the other given therapy for fixed duration (24 doses of WHO MB regimen) (FDT), were compared for relapse rates during treatment and in the post-treatment period. During the follow-up of 980.2 person years in 260 patients treated with FDT, 20 relapses (2.04/100 patient years) were observed. In the other gro...
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One of commonest questions asked by leprosy patients on their completing multidrug therapy (MDT) is, 'Am I cured?' . There are, of course, several different facets to this question, including the risk of subsequent physical deterioration due to damage to anaesthetic hands or feet. But, from the point of view of chemotherapy, the questioner is in effect enquiring whether all the leprosy bacilli ...
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Treatment for multibacillary leprosy is presently performed with a multidrug therapy (MDT) scheme maintained for 2 years. Leprosy treatment however can benefit from the reduction of length. The lack of interferon-gamma (IFN-gamma) production by lepromatous leprosy (LL) patients' lymphocytes lead us to use this cytokine in the treatment of multibacillary leprosy associated with MDT in the treatm...
متن کاملTwelve months fixed duration WHO multidrug therapy for multibacillary leprosy: incidence of relapses in Agra field based cohort study
BACKGROUND & OBJECTIVES The reported low relapse rates after 24 months multidrug therapy (MDT) for multibacillary leprosy (MB) led to the recommendation of reducing duration of therapy to 12 months. However, only a few reports exist on long term follow up data after 12 months fixed duration therapy (FDT). The present study was done to assess the incidence of relapse in MB leprosy patients after...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 2008
ISSN: 2162-8807
DOI: 10.47276/lr.79.3.320